PUBLICATIONS
Recent Peer Reviewed Publications
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Comparative Expression of Soluble, Active Human Kinases in Specialized Bacterial Strains. A Sunderhaus, R Imran, E Enoh, A Adedeji, T Obafemi and MH Abdelaziz#. PLoS ONE (2022) 17(4): e0267226.
Engineering Soluble Artificial Epidermal Growth Factor Receptor Mimics Capable of Spontaneous in vitro dimerization. A Sunderhaus, R Imran, A Goudelock, M Nassar, K Cooper, D Patterson, and MH Abdelaziz#.
Biotechnol. Bioeng. 118 (4) (2021) 1466-1475.
Expression and Purification of Active Human Kinases Using Pichia pastoris as A General-Purpose Host. MH Abdel Aziz#, Y Fan, L Liu, M Moasser, H Fu, N Jura, M Arkin. Prot. Exp. Puri. 179 (2021) 105780.
Onydecalins, Fungal Polyketides with Anti-Histoplasma and Anti-TRP Activity. L Zhenjian, P Sujal, Z Lu, S Beyhan, MH Abdel Aziz, C Reilly, and EW Schmidt. J. Nat. Prod. 81(12) (2018) 2605-11).
Novel Heparin Mimetics Reveal Cooperativity Between Exosite 2 and Sodium-Binding Site of Thrombin. MH Abdel Aziz and UR Desai. Thromb. Res. 165 (2018) 61-67.
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Under Preparation
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The Activity and NH125 Inhibition of VraS Sensor Histidine Kinase from Staphylococcus aureus in Presence of its Cognate Response Regulator, VraR. S Bhattarai, L Marsh, K Knight, L Ali, A Gomez, A Sunderhaus, and MH Abdel Aziz#. Under final revisions.
Expression of Human Kinases in Bacterial Host Systems: A Comprehensive Review. H Sibal, R Imran and MH Abdel Aziz#. Under final revision.
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Book Chapters
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Cardiovascular Agents. UR Desai, R Al-Horani, AY Mehta and MH Abdel Aziz (2013). In The Chemistry of Drugs for Nurse Anesthetists–2nd Edition (Eds. Drs. Lemont B. Kier and Cynthia Schiek), AANA Publishing, Park Ridge, IL.
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Posters/Presentations
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Activation of VraS histidine kinase by T331I mutation linked to antibiotic resistance. Shrijan Bhattarai, Allison Sunderhaus, Lane Marsh, and May H. Abdel Aziz. Selected for “Live Poster” session in the ACS National Meeting. April 10, 2021.
Modulation of VraS Sensor Histidine Kinase Activity and Inhibition in Presence of its Response Regulator VraR. Lane Marsh, Shrijan Bhattarai, Allison Sunderhaus, Paul Epie, and May H. Abdel Aziz. Presented in the Texas Academy of Science. February 27, 2021.
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Characterization of VraS Kinase Involved in Bacterial Resistance. Antonio Gomez, Shrijan Bhattarai, Vivian Ikegbunam, Allison Sunderhaus, and May H. Abdel Aziz. Presented in the UT Tyler Lyceum, Tyler, TX. April 17, 2020. (First place, Graduate Student Poster Award).
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The Cellular Effects of An Allosteric HER2 Homodimerization Inhibitor. Shrijan Bhattarai, Ramsha Imran and May H. Abdel Aziz. Presented in the UT Tyler Lyceum, Tyler, TX. April 17, 2020.
Optimizing the expression of soluble, active human kinases using specialized E.coli strains. R Imran, A Adedeji, T Obafemi, MH Abdel Aziz. Presented in the ACS National Meeting, Philadelphia, PA. March 22, 2020.
Discovering novel anticancer allosteric inhibitors of HER2 homodimerization. H Sibal, O Oyerinde, P Amadi-Ohiri, PD Mosier, MH Abdel Aziz. Presented in the ACS National Meeting, Philadelphia, PA. March 22, 2020
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Discovering Potential Novel Allosteric Inhibitors of HER2 Homodimerization for Treatment of Cancer. PD Mosier and MH Abdel Aziz. Presented in the 1st East Texas Research Conference. Tyler, TX. May 9, 2019.
Optimizing the Expression of Human Heparanase in Insect Cells. E Enoh; H Sibal, R Imran; and MH Abdel Aziz. Presented in the 1st East Texas Research Conference. Tyler, TX. May 9, 2019.
De novo Design and Engineering of Soluble Artificial Kinase Receptor Proteins. K Cooper, M Nassar, MH Abdel Aziz, D Patterson. Presented in the East Texas Research Conference. Tyler, TX. May 9, 2019.
Sulfated low molecular weight lignins bind to a specific pocket in thrombin exosite2. MH Abdel Aziz, BL Henry, PD Mosier, UR Desai. Presented in the 63rd Southeastern Regional Meeting of the ACS. Richmond, VA. October 27, 2011.
Identification of the site of binding of sulfated low molecular weight lignins on thrombin. MH Abdel Aziz, JN Thakkar, BL Henry, A Liang, PD Mosier, UR Desai. The 89th Virginia Academy of Sciences Annual meeting. University of Richmond, Richmond,VA. May 26, 2011.
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